The Roast Beef and Cheddar Sandwich with Horseradish Sauce is a bold, satisfying classic that brings together tender beef, sharp cheddar cheese, and a creamy, zesty horseradish sauce. This sandwich is inspired by traditional American deli favorites, where simple, high-quality ingredients are layered to create big flavor with minimal fuss.
Perfect for lunch, casual dinners, or game-day meals, this sandwich strikes the ideal balance between hearty and indulgent. Whether served warm with melted cheese or cold for a quick bite, it’s a timeless recipe that never disappoints.
Why I Love This Recipe
I love this recipe because it delivers rich, deli-style flavor in a simple homemade sandwich.
The combination of savory roast beef, sharp cheddar, and spicy horseradish sauce creates a bold taste that’s comforting and satisfying. It’s quick to prepare but feels filling and special every time.
Why This Is a Must-Try Dish
- Packed with bold, savory flavor
- Easy and quick to prepare
- Perfect for lunches or casual dinners
- Customizable with different breads and cheeses
- Great balance of creamy, sharp, and spicy
Preparation Time, Cooking Time & Servings
Preparation Time: 10 minutes
Cooking Time: 5–8 minutes (optional, for toasting/melting)
Total Time: 15 minutes
Servings: 2 sandwiches
Calories: Approximately 520 calories per serving
Course: Lunch / Main Dish
Cuisine: American
Ingredients
- 8 oz sliced roast beef (deli-style or leftover roast)
- 4 slices sharp cheddar cheese
- 2 sandwich rolls, hoagie rolls, or rye bread
- 2 tablespoons mayonnaise
- 1–2 teaspoons prepared horseradish (adjust to taste)
- 1 teaspoon Dijon mustard (optional)
- Butter or olive oil, for toasting
- Salt and black pepper, to taste
- Optional toppings: lettuce, tomato slices, caramelized onions
Cooking Directions
- Prepare the horseradish sauce.
- Assemble roast beef and cheddar on bread.
- Toast or warm the sandwich if desired.
- Serve immediately while warm and melty.
Step-by-Step Preparation Method
Step 1: Make the Horseradish Sauce
In a small bowl, mix mayonnaise, prepared horseradish, Dijon mustard (if using), salt, and pepper until smooth. Adjust horseradish to desired heat level.
Step 2: Prepare the Bread
Slice the rolls or bread in half. Lightly butter or brush with olive oil if you plan to toast.
Step 3: Assemble the Sandwich
Layer sliced roast beef evenly on the bottom half of the bread. Top with cheddar cheese slices.
Step 4: Warm the Sandwich (Optional)
Place the sandwich under a broiler or in a skillet until the cheese melts and the bread is lightly toasted.
Step 5: Add Sauce and Finish
Spread horseradish sauce on the top half of the bread. Add optional toppings if desired, close the sandwich, and serve.

How to Serve
Serve the Roast Beef and Cheddar Sandwich warm with the cheese melted for maximum comfort. Pair with fries, potato chips, coleslaw, or a simple green salad. It’s also great with pickles or a cup of soup on the side.
Recipe Tips
- Use high-quality roast beef for best flavor
- Sharp cheddar adds the best contrast
- Warm the beef slightly for a juicier sandwich
- Don’t overdo horseradish—start small
- Toasting the bread adds great texture
Variations
Spicy Version: Add extra horseradish or a dash of hot sauce.
Onion Lover’s: Add caramelized or crispy fried onions.
Swiss Swap: Replace cheddar with Swiss cheese.
Low-Carb Option: Serve open-faced or in lettuce wraps.
Au Jus Style: Serve with warm beef broth for dipping.
Freezing and Storage
Storage:
Store leftover roast beef and horseradish sauce separately in airtight containers in the refrigerator for up to 3 days.
Freezing:
Freezing assembled sandwiches is not recommended. Roast beef alone can be frozen for up to 2 months.
Special Equipment Needed
- Skillet or oven (for toasting)
- Mixing bowl
- Knife and cutting board
Conclusion
The Roast Beef and Cheddar Sandwich with Horseradish Sauce is a hearty, flavor-packed classic that’s easy to make and incredibly satisfying. With tender beef, sharp cheese, and a creamy kick of horseradish, this sandwich delivers comfort and bold taste in every bite. Whether for a quick lunch or a casual dinner, it’s a must-have recipe you’ll return to again and again.
Roast Beef and Cheddar Sandwich with Horseradish Sauce
Description
The Roast Beef and Cheddar Sandwich with Horseradish Sauce is a bold, satisfying classic that brings together tender beef, sharp cheddar cheese, and a creamy, zesty horseradish sauce. This sandwich is inspired by traditional American deli favorites, where simple, high-quality ingredients are layered to create big flavor with minimal fuss.
Ingredients
Instructions
-
Make the Horseradish Sauce : In a small bowl, mix mayonnaise, prepared horseradish, Dijon mustard (if using), salt, and pepper until smooth. Adjust horseradish to desired heat level.
-
Prepare the Bread : Slice the rolls or bread in half. Lightly butter or brush with olive oil if you plan to toast.
-
Assemble the Sandwich : Layer sliced roast beef evenly on the bottom half of the bread. Top with cheddar cheese slices.
-
Warm the Sandwich (Optional) : Place the sandwich under a broiler or in a skillet until the cheese melts and the bread is lightly toasted.
-
Add Sauce and Finish : Spread horseradish sauce on the top half of the bread. Add optional toppings if desired, close the sandwich, and serve.
